nuri77The nuclear receptor Nur77 (also known as TR3 or NGFI-B), encoded by the immediate early gene Nr4a1, belongs to the steroidthyroidretinoid superfamily (Hazel et al.,The mechanism of Nur77 regulating cell survival and apoptosis in CNS. Nur77 mediates cell apoptosis through caspase, endoplasmic reticulum stress, and mitochondrial autophagy, while