Nur77 senses LPS and dsDNA for non-canonical inflammasome

nuri77Nur77 responds to a wide range of physiological molecules and stimuli. 4, 14 These snals quickly induce Nur77 expression and stimulate its transcriptional activity; Nur77Nuclear receptor subfamily 4 group A member 1 (NR4A1; also termed Nur77TR3NGFIB), a member of the nuclear receptor superfamily, is expressed as an early response gene to